Tag Archives: Ocular Terpenes

Terpenes and ocular pathology

How can terpenes affect eye health, vision, and visual perception?

Cannabis might provide performance benefits at low doses through relaxation and possible improvement of auditory and visual perception.

Vision

Cannabis can improve the speed in which the eye responds to dim stimuli. Previous reports have documented an improvement in night vision among Jamaican fishermen after ingestion of a crude tincture of herbal cannabis, while two members of this group noted that Moroccan fishermen and mountain dwellers observe an analogous improvement after smoking kif.

They were able to show that this happened because of Cannabinoid Binding with the CB1 receptor, and inhibiting a protein called NKCC1, which shuttles chloride ions in and out of cells to determine their electrical potential. 

Blood-Flow

Cannabis lowers blood pressure which dilates the blood vessels and increases blood flow throughout the body. Tetrahydrocannabinol (THC), relaxes arterial walls resulting in lower blood pressure and increased blood flow to tissues. In the brain, THC regulates the microvascular environment via dose-dependent dilation of cerebral arterioles

Left Occipital 

Cannabis-induced changes in the left occipital area, a region in the back of the brain that processes visual information. Decreased activation in the right prefrontal, medial and dorsal parietal, and medial cerebellar regions, but greater activation in various frontal, parietal and occipital brain regions during the visual-attention tasks

Macular Degeneration 

The symptoms of macular degeneration revolve around vision. The light-sensitive retina cells deteriorate, leading to blind spots.
Endocannabinoid receptors have been found around the ocular region, cannabis use has been found to reduce inflammation, inhibit vascular endothelial growth factor and lower intraocular pressure. Showing incredible promise for cannabis as a treatment for macular degeneration.

Improve Night-Vision.

Experiments show that cannabinoids reduce the concentration of chloride ions inside the retinal ganglion cells, making them more excitable and more sensitive to light,

This effect is dose-dependent and cannabinoid-mediated at the retinal level.

There’s more research to be conducted, however, the results suggest that some of the compounds in cannabis could potentially be useful for treating diseases such as retinitis pigmentosa and glaucoma, which kill off cells in the retina and gradually cause blindness.

Methods

These treatments can be achieved by both systemic or localized methods. There are several ocular drops being developed for a wide range of conditions. Therapeutic benefits are possible at a dosage that is not subjectively too intoxicating for the patients. 

In order to apply these performance enhancing qualities to products,

The relative contributions of THC, CBD, Other Cannabinoids and Essential Oil Terpenoids to the observed effects, should be cataloged and quantified.

Which terpenes improve vision? Are there terpenes, when inhaled, that can affect visual perception? What is the correct delivery method? Can cannabinoids improve our ability to detect or process illusions? Can terpenes change our perception of color intensity? Do terpenes affect any enzymes associated with the functions of the eye? What terpenes should I use in my product?

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