Linalool Outlined

Linalool 

Linalool is a monoterpene, it has a role as a plant metabolite and is produced by an assortment of plants. Historically used in traditional medicine for its sedative and anti-epileptic properties, many new applications have been found.

Metabolism 

Linalool doesn’t stick around in your body for long and doesn’t accumulateI as it undergoes metabolic modifications including oxygenation and acetylation, which may affect the modulatory efficacy of the generated linalool derivatives.

Uses 

There are many Linalool applications.

It is used as a scent in the majority of perfumed hygiene products. its applications include the formulation of,cosmetics, skin care, hair care, medical care and home care products for its scent and absorption properties.

Anti-Inflammatory and Pain Reducer

Linalool is useful for dampening responses to injury or sickness.

Inflammatory response can be driven by cytokine production. Cytokine regulate function and expression of adenosine. Linalool can increase the adenosine levels in the body, pain-relieving  properties to its elevation of adenosine levels, an inhibitory brain chemical that is notably blocked by caffeine.

Sedative

Linalool can improve sleep and increase energy. 

Adenosine, a chemical that relaxes the mind and serves as a sedative. Inhaled linalool seems to induce sedation without significant impairment in motor abilities

Anti-Epileptic

Linalool is known as a powerful anticonvulsant agent.

The anticonvulsant effects of Linalool can be attributed to both an inhibition of potassium-stimulation and antagonism of NMDA and GABA receptors. gamma-aminobutyric acid (GABA) and N-methyl-D-aspartate (NMDA)are involved in muscle contraction.

Research suggests mostly carbon 8 oxygenated Linalool metabolites positively affect GABAergic currents.

Immune Response

Effects of Linalool on immune functions are currently being studied.

Linalool inhalation has been shown to act as an anxiolytic and may boost immune system performance. A healthier immune system better prepared to fight infection and disease Some research suggests that Linalool can inhibit the development of cancerous tumors and ease the symptoms of a variety of autoimmune disorders. 

Anti-Mosquitos

Linalool can deter mosquitos.

Linalool interacts with an odorant receptor effectively disorienting the mosquito. It is found that a formulation containing monoterpenes and sesquiterpenes is the most effective repellent. 

Anti-Microbial Modulator

Linalool may improve anti-microbial properties.

Chemical analysis revealed that linalool from cumin seed oil were the bioactive compounds responsible for both synergistic antibacterial and antioxidant activities. 

Cardiovascular System

Linalool helps to reduce blood pressure.

Linalool reduces blood pressure due to a direct effect on the vascular smooth muscle leading to vasodilation. Hypotensive actions caused by direct vasodilation coupled with decrease of heart rate.

Anti-Alzheimer

Disease caused by the buildup of brain plaques and cellular tangles. Linalool and other terpenes are being investigated for their role in reducing these symptoms and restoring brain function 

Storage

Due to the oxidation hazard the correct storage and handling of terpenes is very important. Due to the cost, weight, and fragility, glass or ceramic containers are rarely used for packaging, however, the Linalool will have no effect on glass or ceramic packaging. Most suppliers use rust-free stainless steel storage. Other specialized methods of removing oxygen is suggested to reduce oxidation.

Chemical Properties 

Formula: C10H18O

Molar mass: 154.25 g/mol

Density: 858 kg/m³

Boiling point: 198 °C

Chemical Structure

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